A multi-centre study started in KCL, with other sites in Birmingham, Oxford and Newcastle. This study is exploring the efficacy of cognitive remediation therapy in people with bipolar, compared to treatment as usual.
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An EU-funded project aiming to identify early predictors of a good response to lithium in individuals with Bipolar Disorder. 16 sites were involved, forming a multidisciplinary international network of experts.
Team Lithium have a major role in the project, leading on the set up of lithium imaging in key centres. Having developed the ability to chart the distribution of lithium in the brain, this project will permit other centres to conduct cutting edge research with the goal of better predicting response to lithium, and of course studies seeking to understand its mode of action.
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At King's College London, the CfAD focus on mood and anxiety disorders. They are working towards understanding the science related to these illnesses and developing new treatments.
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Collaborating with the University of Edinburgh on a study to better understand the mechanisms behind bipolar disorder, and how lithium works to treat it. One theory is that people with bipolar disorder have an abnormality in the retina of their eyes, making them more sensitive to light. It is possible that lithium works by altering their response to light and regulating circadian rhythms. This study will test whether people with bipolar are hypersensitive to evening light, and whether lithium counteracts this.
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David Cousins is a part of IGSLI, a group that strives to conduct innovative research focused on affective disorders, and lithium. They also aim to be at the front of current developments in medical research and to play an active role in producing change in patient care. IGSLI encourages cooperation internationally across research institutions.
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David Cousins is a part of the ConLiGen. Their main goal is to define the phenotype of lithium response, and to assess all aspects of the pharmacogenetics of lithium treatment in psychiatric disorders. By collaborating, high-quality, well-powered analysis of lithium treatment response data is facilitated.
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