OUR CURRENT STUDIES

R-LiNK

We are part of a large multi centre, multinational research study which aims to identify biomarkers of response to long-term lithium treatment. Funded by the EU Horizon 2020, we established lithium imaging in 6 centres across Europe. Recruitment and data collection has now closed, but we are working on the results and of course the next project.

CRiB2

This is an NHIR funded trial of Cognitive Remediation therapy in Bipolar disorder. It compares a new form of therapy with treatment as usual. The study recruitment will soon close, but we are excited to begin the analysis to see if this treatment could help those with bipolar disorder.

LIPOC

Working with King's College London, we are bringing Point of Care testing for lithium to CNTW NHS Foundation Trust. This study will test whether it is feasibly to monitor lithium levels using a simple finger-prick blood sample. Recruitment will open soo so if you are interested, watch this space.

ILIAD

Early studies have shown that lithium may be effective in preventing the development of Alzheimer's Disease. We are at an early stage of understanding if this is the case, and if so, how. Since it may relate to the amount of lithium in the brain, we are testing whether it is feasible to measure the low levels of lithium in the brain in people with Alzheimer's Disease after a short period of taking a low dose of lithium. This study will soon open to recruitment.

SLIPI-M

Low dose lithium may be a future treatment for neurodegenerative conditions such as Alzheimer's Disease. We have already shown that it is possible to detect lithium in the brain after healthy subject took dietary lithium supplements for one month. This study will repeat the process, but also assessment the effects of lithium on blood markers of inflammation and mitochondrial function. This will help us understand the effects of lithium on the brain and the body.

LIDO

When starting lithium, the dose is usually titrated to the correct levels - progressive increasing in dose with blood measurements each week until the target is reached. We have been developing a Lithium Dose Calculator which show promise in predicting the likely dose for a given person. We hope this will guide the early steps in treatment, reducing the number of steps and blood samples needed.